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Aug 7 – 11, 2023
Novo Nordisk Fonden
Europe/Copenhagen timezone

Topological puzzles in cell biology

Aug 10, 2023, 11:10 AM
50m
Novo Nordisk Fonden

Novo Nordisk Fonden

Tuborg Havnevej 19, 2900 Hellerup

Speaker

Manu Prakash (Stanford)

Description

Recreational mathematics is a century-old field which involves mathematical puzzles and games, often appealing to children and untrained adults, inspiring deep study of the subject. Can a similar analogy be drawn in biology? One place to explore these ideas is the role of geometry and topology (geometric properties invariant to continuous change in shape or size) in biological form and function. Without making any claims of usefulness, in this talk I will explore a wide range of topological and geometrical puzzles in cellular physiology: Can single cells be toroidal in nature? Can cellular geometry (cytoskeleton) explain complex behavior in single cells? Can "Klein bottles" help us understand a fungal pathogen? Do cells get stuck forever in topological traps? Finally, we will reflect on the role of curiosity as an engine for discovery in life sciences.

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